At the outbreak of World War II, Rozka went to Vilna where she became an active Zionist leader, along with Abba Kovner and Vitka Kemper. Together with other young Zionist activists, she formed the United Partisan Organization, which called for armed resistance against the Nazis. After discovering that armed resistance was not practical, she left the ghetto and joined fighters to form partisan groups in the Runinkai forest.
After Vilan was liberated in July 1944, Rozka immigrated to Palestine where she formed the Kibbutz Eilon and the Kibbutz Ein haHoresh with her former partisans. She was also active in establishing educational memorial projects and Holocaust study centers in Israel.